Building upon the strengths of the best-selling first edition, Histamine and H1-Antihistamines in Allergic Disease, Second Edition presents the latest advances and current research in histamine, histamine receptors, and H1-antihistamines for practical application in allergy, immunology, dermatology, otolaryngology, and pulmonology.Contains over 2000 contemporary references-300 more than the first edition!This Second Edition offers new chapters detailing cost-effective techniques to treat and manage allergic rhinoconjunctivitis, urticaria, angioedema, atopic dermatitis, asthma, and anaphylaxis the use of nonsedating antihistamines in care of the elderly the safety of specific antihistamines during pregnancy and lactation quality-of-life comparisons among different H1-antihistamines used in the treatment of allergic rhinitisand provides completely revised and expanded material describingthe role of histamine in the pathogenesis of asthma regimens for the prevention of anaphylaxis and anaphylactoid reactions the potential of combined antihistamine and antileukotriene therapyWith contributions from more than 20 esteemed international authorities, the Second Edition of Histamine and H1-Antihistamines in Allergic Disease is an in-depth guide suitable for allergists, immunologists, pulmonologists, respiratory specialists, dermatologists, otolaryngologists, pharmacologists, and graduate students in these disciplines.